Pioneering Discoveries Profound Change

Meet Our Scientists

  • Xiaozhe Han

    Associate Member of the Staff
    Xiaozhe Han is interested in the host immune response in periodontal disease tissue destruction, particularly in the area of osteoimmunology, the interaction between the immune system and bone metabolism and its role in inflammatory bone destruction. He focuses on a specific immune cell su...
  • Chung-Jung Chiu

    Assistant Investigator
    Our research interest includes the remote effects of oral microbiota and oral health policy. Through collaborating with multidisciplinary experts, we aim to take care of oral health as a whole of human body. The oral cavity has a myriad of resident microbiota and periodontal microbiota is...
  • J. Max Goodson

    Emeritus Professor
    Inventor, renowned researcher, until recently Director of Clinical Research, and Senior Member of Staff at the Forsyth Institute since 1976. Dr. Goodson is an Associate Clinical Professor in the Department of Oral Medicine, Infection, and Immunity at the Harvard School of Dental Medicine. ...
  • Jing Zhou

    Assistant Investigator
    Sjӧgren’s syndrome is a prevalent and systemic autoimmune disorder characterized by immune system attacking self-salivary and lacrimal glands, leading to xerostomia and keratoconjunctivitis sicca as major clinical manifestations. This disease also can cause an increased incidence of dental...
  • Megan Pugach

    Assistant Member of the Staff
    Forsyth Profile — audio interview Many people, at one time or another, have a dream that involves their teeth disintegrating. This common dream is said to represent fears and anxiety. For people with amelogenesis imperfecta (AI) this nightmare can become a reality. AI is actually a group o...
  • Bruce J. Paster

    Senior Member of the Staff
    The Paster lab provides researchers with a scientific “canary in a coal” mine. With a one-of-a-kind service, the Human Oral Microbe Identification Microarray, Bruce Paster is using technology to probe DNA samples to see if they contain healthy or potentially harmful bacteria. HOMIM provide...
  • Susan Rittling

    Senior Investigator
    Root canals, which treat endodontic infections, are one of the most common dental procedures. Yet, up to 15% of root canals fail, and patients require retreatment, or tooth replacement.  Susan Rittling is trying to understand why these infections are so difficult to treat and to ultimately...
  • Anne C.R. Tanner

    Emerita Professor
    Anne Tanner is a Forsyth dentist/microbiologist whose research interests have encompassed periodontal infections and dental caries (cavities). Her pivotal studies in anaerobic microbiology led to the description of several major periodontal pathogens including Bacteroides forsythus, which...
  • Isabel Fernández Escapa

    Assistant Investigator
    Research on the microbiome has bloomed during the last two decades, bringing together microbiologists, immunologists, epidemiologists, statisticians, and bioinformaticians in a complex field that requires researchers to be constantly ahead of new technological developments. As Director of...
  • Alpdogan Kantarci

    Associate Member of the Staff
    Through the integration of clinical and laboratory research, Alpdogan (Alp) Kantarci focuses on helping people live healthier lives with healthy mouths. “I see patients in the clinic, and when I work in the laboratory, I am keeping those patients front and center,” said Kantarci. “How can...
  • Hatice Hasturk

    Associate Member of the Staff
    As a dentist and specialist (periodontist), Hatice Hasturk’s work mainly involves the oral cavity, but she is interested in much more than just improving dental care. She is working to understand the link between oral diseases and how they can affect the rest of the body.  Specifically, Ha...
  • Jacqueline Starr

    Associate Member of the Staff
    Jackie Starr wears two hats, one as Director of Forsyth’s Epidemiology and Biostatistics Core, and the other as a principal investigator. As Director of the core, she plays a key support role for much of Forsyth’s research. She helps Forsyth investigators design their research studies. She...
  • Mark Cayabyab

    Associate Investigator
    Mark Cayabyab’s research focuses on vaccine development, as well as the role of innate immunity in the induction of protective memory immune responses. The overall goal of this research is to develop effective vaccines against infectious diseases. Forsyth has long been a leader in infectio...
  • Kerry Maguire

    Associate Investigator
    Kerry Maguire’s work links The Forsyth Institute’s past with its future. As the Program Director of ForsythKids, Maguire is on the front line delivering dental care to underserved children. The program is a two-way street, with ForsythKids delivering community-based prevention based on res...
  • Tsute (George) Chen

    Associate Investigator
    Forsyth Profile — audio interview Scientific research today is truly interdisciplinary—computer science, statistics, mathematics and engineering all play an important role in the life sciences. Tsute Chen’s work illustrates how far research has evolved and its integration with different di...
  • Qing Yu

    Associate Member of the Staff
    Forsyth Profile — audio interview  Qing Yu is interested in understanding the immunological mechanisms underlying the pathogenesis of several systemic autoimmune diseases that affect oral health, in order to develop effective and targeted therapeutic approaches for these diseases. One of h...
  • Tingxi Wu

    Assistant Member of the Staff
    Tingxi Wu, DDS, PhD Assistant Member of the Staff Director, Orthodontic & Craniofacial Development Research
  • Markus Hardt

    Assistant Member of the Staff
    Markus Hardt studies the molecular mechanisms of disease, with the goal of finding pathways that lead to new diagnostics and therapeutics. Hardt is particularly interested in cancer pain. Effective treatment of pain remains a critical unmet goal in cancer therapy. Increased life expectanci...
  • Mary Tavares

    Senior Investigator
    Mary Tavares’ research is closely linked to Forsyth’s founding mission. With a focus on both clinical and public health research, Tavares is interested in bringing about policy change that has an impact on dental health. Her ultimate goal is to ensure better oral health and overall wellnes...
  • Xuesong He

    Associate Member of Staff
    Forsyth Profile — audio interview Trained as a dentist and microbiologist, Xuesong He started his academic career by studying regulation of virulence gene expression in some of the main oral pathogens, including the cariogenic bacterium Streptococcus mutans, and periodontal pathogen, Fusob...
  • Thomas E. Van Dyke

    Senior Member of Staff
    Forsyth Profile — audio interview When Tom Van Dyke was asked what future innovation at Forsyth would spark an invitation to give a TED Talk, he had an interesting answer. “We’d be invited for doing one thing but the real breakthrough− and our message−would be something else entirely.  We’...
  • Felicitas Bidlack

    Associate Member of the Staff
    Forsyth Profile — audio interview With a background in biology and anthropology, Felicitas Bidlack is interested in tooth formation, evolution, and the processes that drive mineral formation, and de-and re-mineralization of teeth. Her primary goal is to integrate her broad background into...
  • Yang Hu

    Assistant Investigator
    Periodontitis is an important public health problem among adults in the United States with major economic cost for prevention and treatment. It also has a significant impact on quality of life, un-controlled periodontitis can cause extensive tooth loss, jaw bone deterioration and increased...
  • Katherine P. Lemon

    Associate Member of the Staff
    Bacteria live on us, “in” us, and on surfaces all around us. Katherine Lemon, a pediatric infectious disease specialist, is trying to figure out how the good bacteria in the nose and throat help keep the “bad” bacteria out or, at least, under control. In addition to her work in the lab at...
  • Floyd Dewhirst

    Senior Member of the Staff
    Floyd Dewhirst was deciphering the oral microbiome before the term microbiome was created.  Dewhirst’s primary research focus has been to define the diversity, genetic capability and pathogenic potential of organisms present in the human oral cavity. Dewhirst has used sequencing of the 16S...
  • Pramod M. Soparkar

    Senior Investigator
    For almost 30 years, Pramod (Bob) Soparkar has been bringing Forsyth’s expertise to bear in the Middle East, while setting the paradigm for children’s oral health in Kuwait. In the 1980s, Soparkar and his colleagues at Forsyth were invited to Kuwait to establish a comprehensive oral health...
  • Gary Borisy

    Senior Investigator
    A recent collaborator with scientists at Forsyth, Gary Borisy, a member of the National Academy of Sciences, joined the Department of Microbiology in 2013. Although much of his previous scientific work has focused on mammalian cells, Borisy has recently developed a unique methodology to si...
  • Margaret J. Duncan

    Emerita Professor
    Research in the Duncan lab focuses on how bacteria respond to environmental signals and become disease causing (‘pathogenic’).  Humans live peacefully with billions of microorganisms on and in their bodies. In reality, this benign coexistence is based on a dynamic and delicate equilibrium,...
  • Martin A. Taubman

    Emeritus Professor
    Dental enamel is the hardest substance produced by the human body, but it does not start out that way. When it first begins forming on an unerupted developing tooth, enamel tissue is as soft as cheese. As the enamel matures, it becomes progressively harder and develops ultimately into a mi...
  • Daniel J. Smith

    Emeritus Professor
    The outstanding success of vaccines in combating infectious diseases is now a familiar story. The Smith lab developed vaccines as a strategy to prevent some of the most common of all human infections, those leading to tooth decay. They studied how and when young children acquire these infe...

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