Dr. Trackman joined the Forsyth Institute in November of 2020 from Boston University Henry M. Goldman School of Dental Medicine, where he has been a faculty member since 1992 and where he served as the Director of Oral Biology Graduate Programs. He is best known for his work in the understanding of the biosynthesis and […] (Dec 03, 2021)
Our lab focuses on developing functional biomaterials for dental and craniofacial applications. One research direction is applying stimuli-responsive smart biomaterials for dental caries and periodontitis treatment and prevention. Another focus of the lab is applying enzymatically and hydrolytically stable resin networks to make multifunctional and durable dental resin composites. Fields of Interest: Biomaterials, material-cell interaction, […] (Nov 04, 2021)
Morphogenetic Signaling Network in Development and Disease We are interested in the mechanisms that support embryonic morphogenesis, tissue homeostasis, disease pathogenesis, and organ repair and regeneration. Focusing initially on Wnt as one of the most prevalent signaling pathways in developmental biology, we are establishing how Wnt signaling and its crosstalk with other pathways control pluripotency […] (Jun 29, 2021)
Understanding human health and disease has driven research in the Dewhirst lab for the past 40 years. Systemic human health is directly linked to the health of tissues in the oral cavity. The mouth is the gateway to the gastrointestinal tract, and oral sites are easily examined and sampled to address basic biological questions. The […] (Apr 01, 2020)
Ultrasmall Bacteria Determining how bacteria interact and influence one another’s behavior is a fundamental goal of microbiology. However, these processes remain poorly understood even in the simplest arrangement of microbial communities. Saccharibacteria (TM7) is a symbiotic bacterium that grow and persist on its host-bacteria, a relationship that is rarely studied due to lack of known […] (Apr 01, 2020)
Mineralized tissue research: Tooth enamel and dentin Teeth are remarkable in that they are formed to last for a lifetime to withstand extreme variations of temperature, acidity and mechanical stress. Advanced engineering approaches attempt to mimic the natural makeup of teeth, with a very hard shell on a softer core that is anchored in the […] (Mar 13, 2020)
