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Forsyth Institute and Sherlock Biosciences partner to advance research and technology of human biomarkers in the oral cavity

The Forsyth Institute has entered into a strategic collaboration with Sherlock Biosciences, an Engineering Biology company dedicated to making diagnostic testing better, faster and more affordable. The partnership is focused on research, development, and commercialization of products and services for detection of human biomarkers in the oral cavity and other oral health applications. The oral […] (May 17, 2021)

Forsyth contributes to reconstructing oldest oral microbiome ever sequenced from a 100,000-year-old Neanderthal

In a new study published in the Proceedings of the National Academy of Sciences, researchers from 41 institutions in 13 countries collaborated to reconstruct the oral microbiomes of Neanderthals, primates, and humans, including the oldest oral microbiome ever sequenced from a 100,000-year-old Neanderthal. Scientists analyzed fossilized dental plaque of humans and Neanderthals and compared it to plaque […] (May 12, 2021)

Periodontal disease increases risk of major cardiovascular events

People with periodontitis are at higher risk of experiencing major cardiovascular events, according to new research from Forsyth Institute and Harvard University scientists and colleagues. In a longitudinal study published recently in the Journal of Periodontology, Dr. Thomas Van Dyke, Senior Member of Staff at Forsyth, Dr. Ahmed Tawakol of Massachusetts General Hospital, and their […] (Feb 21, 2021)

To understand periodontal disease, researchers examine the surprising behavior of T cells

In diseases characterized by bone loss—such as periodontitis, rheumatoid arthritis, and osteoporosis—there is a lot that scientists still don’t understand. What is the role of the immune response in the process? What happens to the regulatory mechanisms that protect bone? In a paper published recently in Scientific Reports, researchers from the Forsyth Institute and the […] (Jan 11, 2021)

Forsyth launches new Forsyth Oral Microbiome Core (FOMC)

The Forsyth Institute is now offering Next Generation Sequencing (NGS) and comprehensive data analyses and interpretation for 16S rRNA gene amplicon sequences and other big data sequence applications through the new Forsyth Oral Microbiome Core (FOMC). Analyses of previously obtained sequences are also offered. Many investigators are familiar with the Human Oral Microbe Identification using Next Generation Sequencing […] (Nov 10, 2020)

With schools closed due to COVID-19, thousands of students cut off from dental care

When schools across Massachusetts closed in light of the COVID-19 pandemic, thousands of students lost access to dental care. The ForsythKids program responded by hosting pop-up clinics at community centers across the state. Our efforts were featured in the Boston Globe today: On Tuesday, ForsythKids ― a mobile, school-based oral health program that provides preventive care in […] (Oct 19, 2020)

The Forsyth Institute serving as a critical resource for COVID-19 saliva diagnostic test development

As a world leader in oral biology and salivary diagnostics, the Forsyth Institute is working with the National Institutes of Health (NIH) Rapid Acceleration of Diagnostics (RADx) initiative as an advisor and critical resource in the effort to develop and eventually deploy millions of accurate, rapid COVID-19 point-of-care tests used daily in schools, colleges, universities, and […] (Aug 25, 2020)